Amphonex 50mg injection (liposomal Amphotericin B [50mg])

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AMPHONEX 50MG


Amphonex 50mg injection

Description:-

Amphonex 50 mg Injection is an antifungal medicine used to treat serious and potentially life-threatening infections caused by different fungal species. The liposomal form of this medicine has been shown to be less nephrotoxic than the conventional form. Incidences of infusion-related adverse reactions associated with the liposomal form are also fewer than that of the conventional form.

Substitutes:-

List of substitutes for Amphonex 50 mg Injection

Ambisome 50 mg Injection

Abbott Healthcare Pvt. Ltd.

Amphogard 50 mg Injection

Zydus Cadila

Hospicin B 50 mg Injection

Alkem Laboratories Ltd.

Lambin Lyophilised 50 mg Injection

Sun Pharma Laboratories Ltd.

Phosome 50 mg Injection

Cipla Ltd. 



Side effects

Major & minor side effects for Amphonex 50 mg Injection

•Irregular heart beat

•Fever and chills

•Diarrhea

•Decreased potassium levels

•Anemia

•Cough

•Abdominal pain

•Headache

•Pain at injection site

•Nausea and Vomiting

•Chest pain 

Uses of Amphonex 50 mg Injection

Invasive Aspergillosis

This medicine is used for the treatment of infections caused by fungi of the Aspergillus species that tend to spread quickly.

Candidemia

This medicine is used for the treatment of candidemia, a condition where the fungi of the Candida species are present in the blood.

Cryptococcosis

This medicine is used for the treatment of fungal infections caused by Cryptococcus species.

Febrile Neutropenia

This medicine is used to treat the development of fever in patients with neutropenia (low number of neutrophils in the blood). 



Warnings:-

Warnings for special population

Pregnancy

This medicine is recommended for use in pregnant women only if absolutely necessary. Discuss all the risks and benefits with your doctor before using this medicine.

Breast-feeding

This medicine is relatively safe for use in breastfeeding women. However, all the risks and benefits should be discussed with the doctor before using this medicine.

Anaphylaxis

This medicine may cause serious anaphylactic reactions. Appropriate corrective measures should be undertaken in the event of any anaphylactic reactions. Therapy may be discontinued based on the clinical condition.

Noninvasive fungal infections

This medicine is not recommended to treat noninvasive fungal infections in patients with normal neutrophil counts.


This medicine may cause infusion reactions such as a headache, fever, chills, loss of appetite, nausea, vomiting, breathing problems, or dizziness with the first few doses. These reactions usually diminish with subsequent doses. 


Dosage

Missed Dose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

General Instructions

This medicine should be administered only by a qualified healthcare professional. Carefully follow all the instructions given by your doctor. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. 


What is Amphonex Injection used for?

Amphonex 50mg Injection is an antifungal medication. It is used in the treatment of severe fungal infections and leishmaniasis. It kills fungi by destroying the fungal cell membrane. This way it helps treat the condition. 

What is liposomal Injection?

A drug preparation that contains the active drug inside very tiny, fat-like particles. This form is easier for the body to absorb and allows more drug to get to the target area of the body, such as a tumor. 

How do you make Amphonex?

Administration and Dosage: Instruction for use: Reconstitute each vial of AMPHONEXTM with 12mL of Water for Injection and shake the vial vigorously till a yellow uniform translucent solution is obtained. Amphotericin B content in this reconstituted solution is about 4mg/mL. 



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