IVABRAD 5 TABLES 5MG



IVABRADINE

 The dose will depend on what you are being treated for. Since the treatment for angina or heart failure is usually life-long, you should not stop using it without talking to your doctor. It should be taken with food at the same time each day. If you take too much in one go, your heart could slow down too much and make you feel breathless or tired. If this happens, call a doctor.


The most common side effects are temporary brightness in your vision and changes to your heart function. You may also experience uncontrolled blood pressure, headache, dizziness, and blurred vision. Some side effects such as fainting and significant changes to your heartbeat may be very serious and may need urgent medical attention. Avoid driving until you know how this medicine will affect you.



Do not use Ivabrad 5 Tablet if you have severe liver disease, have a low resting heart rate, or a heart rhythm disorder. This medicine is also not suitable if you have very low blood pressure and heart failure that has recently become worse. This medicine interacts with certain other medicines used to treat high blood pressure, fungal infections, and HIV. Do not take it if you are pregnant, trying to become pregnant, or breastfeeding. 

Ivabradine is used to treat adults who have chronic heart failure to reduce their risk of hospitalization for worsening heart failure. It is also used to treat heart failure in children 6 months of age and older who have stable heart failure, with symptoms, caused by an enlarged heart (dilated cardiomyopathy).



This medicine is available only with your doctor's prescription.


This product is available in the following dosage forms:


•Solution
•Tablet

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of ivabradine in children younger than 6 months of age. Safety and efficacy have not been established.


Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ivabradine in the elderly.


Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


•Bepridil

•Boceprevir

•Cisapride

•Clarithromycin

•Cobicistat

•Conivaptan

•Dronedarone

•Fluconazole

•Idelalisib

•Indinavir

•Itraconazole

•Ketoconazole

•Lefamulin

•Mesoridazine

•Nefazodone

•Nelfinavir

•Pimozide

•Piperaquine

•Posaconazole

•Ritonavir

•Saquinavir

•Sparfloxacin

•Telaprevir

•Telithromycin

•Terfenadine

•Thioridazine

•Voriconazole

•Ziprasidone 


Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Throw away any unused oral liquid.


Precautions

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects.


Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.


Do not use this medicine if you are also using clarithromycin (Biaxin®), itraconazole (Sporanox®), ketoconazole (Nizoral®), nefazodone (Serzone®), nelfinavir (Viracept®), or telithromycin (Ketek®). Using these medicines together may cause serious unwanted effects.


This medicine may increase your risk for heart rhythm problems, including atrial fibrillation and bradycardia. Check with your doctor right away if you have fast, slow, or irregular heartbeat, dizziness, fainting, or trouble breathing while using this medicine.


This medicine may cause temporary visual brightness, usually caused by sudden changes in light (luminous phenomena or phosphenes). This may happen within the first 2 months of treatment with this medicine. Use caution when driving or using machines where sudden changes in light can happen, especially when driving at night.


Do not take other medicines unless thy have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements.


Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur.

More common

Blurred vision
chest pain or discomfort
fast or irregular heartbeat
headache
lightheadedness, dizziness, or fainting
nervousness
pounding in the ears
slow or irregular heartbeat
unusual tiredness
Incidence not known
Confusion
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
hives or welts, itching, or skin rash
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
sweating

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common

Seeing flashes of light
Incidence not known
Double vision
feeling of constant movement of self or surroundings
flushing or redness of the skin
seeing double
sensation of spinning
trouble seeing
unusually warm skin 

What is ivabradine?

Ivabradine works by affecting your heart's electrical activity in order to slow the heart rate.

Ivabradine is used in adults with chronic heart failure, to help lower the risk of needing to be hospitalized when symptoms get worse.

Ivabradine is also used in children at least 6 months old who have stable heart failure caused by an enlarged heart.

Ivabradine may also be used for purposes not listed in this medication guide. 



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